Jeff has extensive experience in pharma (20+ years) that includes regulatory compliance, quality assurance, discovery R&D, and technical operations. He focuses on cloud computing technologies (IaaS, code-managed architectures, transformation of legacy workflows) and their applications to biomedical modeling and simulation. He is also interested in any technology that streamlines the company’s scientific or business processes. Jeff directs the information systems and business operations for MetrumRG.
Timothy Bergsma, William Knebel, Daniel Polhamus, Jeffrey T. Hane, Marc R. Gastonguay. A Cloud-Based Cluster Computing Platform for Pharmacometric Applications. ACoP 2013.
Jeffrey Hane, Adam Kraut. Building a Scalable Pharmacometrics Platform in the Cloud. Presented at BioIT World Conference and Expo, Boston, MA (April 23-25, 2012)
Two Guys and a Credit Card: Metrum’s Amazon Cloud Makeover – A case study in transferring a life sciences IT infrastructure fully into the cloud. Bio-IT World (Feb 14, 2012). K. Davies
Bergsma T, Fisher J, Gastonguay MR, Hane J, Knebel W, Riggs MM, Rogers JA. Systematic Review of Versioned Files for Modeling and Simulation Quality Control: The“review” R Package. Presented at ACOP 2011, San Diego, CA.
Knebel W, Bergsma TT, Dagdigian C, Hane J, Gastonguay MR. Utilizing NONMEM 7 and the Intel Fortran Compiler in a Distributed Computing Environment. PAGE 2010.
Timothy Bergsma, Jeffrey Hall, Michael S. Smith, Malaz A. AbuTarif, David R. Taft, William Knebel, Joseph Hebert, James Rogers, Jeffrey T. Hane, and Marc R. Gastonguay. Development and Pilot Evaluation of a High-Performance Computing System for Web-Based Deployment of Pharmacometrics Applications in a Multi-User Training Environment. ACOP 2009.
Knebel B, Bergsma T, Gibiansky L, Hane JT, Gastonguay MR. NMQual: A Tool to Automate Installation and Facilitate Qualification of NONMEM. PAGE Annual Meeting: Abstracts, 2005.
Gastonguay MR and Hane JT. The Importance of the Simulation Expectation as a Goodness of Fit Diagnostic for Categorical Population Pharmacodynamic Models. The AAPS Journal; 6(S1), Abstract W4355, 2004.