Evaluating Conditional Exchangeability Assumptions for Bayesian Borrowing, With Application to Pediatric Extrapolation

Presented at the Graybill Conference 2024. Dr. Jim Rogers from MetrumRG as he demonstrates the application of causal selection diagrams as a statistical consulting tool for Bayesian prior elicitation. Bayesian dynamic borrowing is an increasingly important methodology in pediatric extrapolation, and its successful application requires quantitative scientists who can bridge the gap between qualitative notions of “similarity” and formal statistical notions of “exchangeability.”