Exposure-Response Modeling and Simulation to Support Evaluation of Efficacious and Safe Exposure and Dose Range for Asfotase Alfa in Patients With Hypophosphatasia

Pradhan RS, Gastonguay MR, Gao X, Monteleone JPR, Lathia CD, Fisher J, Godfrey C, Dirks NL, Melian A, Thompson DD.  Poster presented at ASBMR 2015 American Society for Bone and Mineral Research’s Annual Meeting. 9-12 October 2015.