Kyle T. Baron, Pharm.D., Ph.D.

Group Leader PKPD, Principal Scientist II

Kyle joined MetrumRG in 2010 after receiving his Pharm.D. and Ph.D. in  Experimental and Clinical Pharmacology from the University of Minnesota. As a member of our translational and systems pharmacology group, Kyle has worked to support sponsor development programs in a variety of therapeutic areas, including chronic hepatitis C infection, HIV, calcium homeostasis and bone health, type-2 diabetes, and cystic fibrosis.  

Kyle is the developer and maintainer of mrgsolve (https://mrgsolve.github.io) and also leads workshops at all levels to guide other M&S scientists in the effective use of this simulation tool in PKPD, PBPK, and QSP modeling. Kyle also serves as adjunct faculty in Experimental and Clinical Pharmacology at the University of Minnesota.  

Recent publications by this scientist

Landmark and longitudinal exposure-response analyses for multiple efficacy and safety endpoints to justify the clinical dose of valemetostat for adult T-cell leukemia/lymphoma

December 15, 2022

Masato Fukae, Kyle Baron, James Rogers, Ramon Garcia, Masaya Tachibana, John Mondick, Takako Shimizu. Poster presented at 2022 American Conference on Pharmacometrics (ACoP13). 30 October – November 2 2022. Poster M-026

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Simultaneous population pharmacokinetic analysis of total and unbound valemetostat in patients with non Hodgkin lymphoma to quantify the effect of the binding protein, alpha 1 acid glycoprotein

December 15, 2022

Masato Fukae, Kyle Baron, Masaya Tachibana, John Mondick, Takako Shimizu. Poster presented at 2022 American Conference on Pharmacometrics (ACoP13). 30 October – November 2 2022. Poster M-030

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A showcase of open-source tools for scalable, reproducible PMx workflows

October 31, 2022

Kyle Baron, Sam Callisto, Seth Green, Matthew Riggs. A showcase of open-source tools for scalable, reproducible PMx workflows. Pre Meeting Workshop presented at 2022 American Conference on Pharmacometrics (ACoP13). 30 October 2022.

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