Marc R. Gastonguay, Ph.D.

Chief Executive Officer

For the last 20 years, Marc has been applying mathematical M&S techniques to problems in clinical pharmacology and drug development across industrial, government, and academic settings. Marc provides the scientific and thought leadership for MetrumRG.

Recent publications by this scientist

Midazolam dose optimization in critically ill pediatric patients with acute respiratory failure: A population pharmacokinetic-pharmacogenomic study

January 30, 2019

Zuppa AF, Conrado DJ, Zane NR, Curley MAQ, Bradfield J, Hakonarson H, Gastonguay MS, Moorthy G, Prodell J, Gastonguay MR. Crit Care Med [Internet]. 2019 Jan 21; Available from:

Download PDF

Vedolizumab exposure levels and clinical outcomes in ulcerative colitis: determining the potential for dose optimisation

January 29, 2019

Osterman MT, Rosario M, Lasch K, Barocas M, Wilbur JD, Dirks NL, Gastonguay MR. Aliment Pharmacol Ther. 49(4):408–18. February 2019.

Download PDF

A latent variable disease progression model for Duchenne muscular dystrophy

October 9, 2018

Hajjar J. Poster presented at 2018 American Conference on Pharmacometrics (ACoP9). San Diego, CA. 9 Oct 2018. Abstract #T-011.

Download PDF