Ahmed Elmokadem, Ph.D.

Senior Scientist II

Ahmed earned his PhD in Biomedical Sciences from the University of Connecticut. His thesis work revolved around building statistical models to solve problems with super-resolution imaging. Other fields of experience include systems biology and pharmacokinetics. More recently, he focused on developing physiologically-based pharmacokinetic (PBPK) models to get a better mechanistic understanding of drugs’ pharmacokinetics.

Recent publications by this scientist

Open-Science Immuno-Oncology QSP Modeling Using Open-Source Julia Solvers

July 28, 2023

As Julia usage continues to grow within regulated biomedical environments, it is vital to ensure analyses are traceable and reproducible. Conducting analyses in an open-science manner is also critical to expand the adoption of Julia and to facilitate the infrastructure growth of Julia as an accessible ecosystem. A step-by-step model-building example of a classic monoclonal antibody-drug conjugate PBPK/tumor dynamics system illustrates how to develop such a reproducible open-science framework.

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Open-Source Bayesian Hierarchical PBPK Modeling in Julia

July 27, 2023

Demonstrates a Bayesian analysis workflow in Julia for an ODE-based model using PBPK modeling as an illustrative example.

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Bayesian PBPK Modeling using R/Stan/Torsten and Julia/SciML/Turing.jl

January 23, 2023

Ahmed Elmokadem, Yi Zhang, Timothy Knab, William R. Gillespie. CPT Pharmacometrics Syst Pharmacol.  January, 20 2023. doi:10.1002/psp4.12926

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