Katherine Kay, Ph.D.

Research Scientist & Reporting Specialist I

Katherine joined Metrum in August 2018 as a Research Scientist. Katherine completed her Ph.D at Liverpool School of Tropical Medicine (LSTM), University of Liverpool, UK. Her dissertation work involved developing and implementing pharmacokinetic-pharmacodynamic (PK-PD) models of antimalarial drug action. In collaboration with the Swiss Tropical and Public Health Institute (Swiss TPH), Katherine translated these models of drug action into their open-source simulation platform of malaria epidemiology and control, “OpenMalaria”. Katherine continued to collaborate with Swiss TPH as a post-doctoral research associate based at LSTM. Her work extended antimalarial PK-PD model methodology to investigate drug resistance and to optimize dosing regimens in malaria treatment, and contributed to ongoing insecticide resistance modeling.

In 2015, Katherine moved to the University at Buffalo, NY, USA, where she developed a physiologically-based pharmacokinetic (PBPK) model to characterize the physiological structure of the vaginal space and the absorption/distribution of vaginally administered drugs. The model specifically focused on the administration of antiretroviral compounds delivered via either a ring or film formulation and aimed at optimizing the probability of success of vaginally administered antiretroviral drugs.

Recent publications by this scientist

Incorporating genetic selection into individual‐based models of malaria and other infectious diseases

November 30, 2020

Hastings, IMHardy, DKay, KSharma, REvol Appl2020132723– 2739https://doi.org/10.1111/eva.13077

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Modeling and simulation of lumefantrine pharmacokinetics in HIV-infected and HIV-uninfected children with malaria and the role of lumefantrine exposure as a potential driver of drug resistance

November 16, 2020

Kay K, Goodwin J, Mwebaza N, Ruiz A, Ehrlich H, Ou J, Freeman T, Wade M, Huang L, Wang K, Li F, Aweeka FT, Riggs M, Kajubi R, Parikh S.  Presented at the annual meeting of the American Society of Tropical Medicine and Hygiene, October 16-18, 2020.

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Improving Methods for Analyzing Antimalarial Drug Efficacy Trials: Molecular Correction Based on Length-Polymorphic Markers msp-1, msp-2, and glurp

September 14, 2019

Presentation by Katherine Kay Ph.D at R/Medicine. Boston, MA. 14 September 2019.


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